Like all blood cells, white blood cells produced in bone marrow. They develop from stem (precursors) of mature cells, which over time in one of the five main types of white blood cells, neutrophils, lymphocytes, monocytes, eosinophils and basophils.
As a rule, people produce about 100 billion white blood cells in the day. The number of white blood cells in a certain amount of blood is expressed in cells at microliter of blood. Total white blood cells, usually ranging between 4000 and 11000 cells per microliter. The share of each of the five main types of white blood cells, and the total number of cells of each type can be identified by reference to the amount of blood.
Too few or too many white blood cells indicates the disorder. Leukopenia, reducing the number of white blood cells less than 4000 cells per microliter of blood, makes people more susceptible to infections. Leukocytosis, an increase in the number of white blood cells in more than 11,000 cells per microliter of blood, may result from the normal reaction of body to help fight infection. Nevertheless, the increase in the number of white blood cells can also result when the regulation of white blood cell development is broken and immature or abnormal cells in the blood is discarded.
In some white blood cell disorders include only one of five types of white blood cells. Other disorders may be associated with several types, or all five types. Diseases of neutrophils and lymphocytes, are the most common disorder. Diseases associated with monocytes and eosinophils are less common, as well as disorders associated basophils rare.